Medicago sativa  
 

 

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Botanical Name : Medicago sativa
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Chemical components : 
Vitamins A, C, E, and K, minerals, and trace elements are present in alfalfa. The amounts of each are unclear, and any benefits or toxicities due to these constituents remain unknown. Alfalfa contains coumestrol, a phytoestrogen that has been isolated from three commercially available alfalfa products, and in vitro may have a role as a low-density lipoprotein (LDL) antioxidant. Alfalfa saponins rather than alfalfa fiber appear to be responsible for the reduction of cholesterol absorption. Flavonoids have also been isolated from alfalfa. Manganese, found in relatively high concentrations in alfalfa, has been proposed as a possible cause of hypoglycemia in one case-report. Immunoreactive thyrotropin-releasing hormone-like material has been found in alfalfa in significant amounts, although its biological action is unknown. 1,2-dimethylhydrazine, a carcinogen, binds to alfalfa when colon pH is between, and alfalfa has been proposed as possessing protective properties against chemically-induced colon cancer.
Effective Ingredients: 
 

 
Therapeutic uses : Alfalfa may possess anti-microbial properties. G2, 2-beta-hydroxy-3-beta-O- (beta-D-glucopyranosyl)-delta 12-oleanene-23, 28-dionic acid, has been isolated from alfalfa roots and has been shown in vitro to possess a high degree of activity against Cryptococcus neoformans (MIC 2mcg/mL). G2 exhibits activity against a wide range of yeast strains, and appears to induce lethal ion leakage from yeast cells. Medicagenic acid, hederagenin glycosides, and soyasapogenols may contribute to the antifungal actions of alfalfa, including against Aspergillus niger, Candida albicans, and Candida tropicalis.
Cholesterol-lowering effects; a study in monkeys found that monkeys fed alfalfa saponins had decreased cholesterolemia without changes in high-density lipoprotein (HDL) when compared to monkeys not fed alfalfa saponins. It was also noted that alfalfa saponins decrease intestinal absorption and increase fecal excretion of cholesterol, a finding also reported in rats. Alfalfa has been shown to prevent the expected rise in cholesterol associated with intake of a high cholesterol diet in monkeys. Alfalfa reduces lipid levels in plasma and tissues more effectively than D-thyroxin and pyrimidine, but not as effectively as cholestyramine or diets completely void of cholesterol. Similar cholesterol-lowering effects have been observed in rabbits. Rabbits with an ileal bypass required less alfalfa to prevent hypercholesterolemia than rabbits with normal gut length, alfalfa was an effective adjuvant to partial ideal bypass in the treatment of hypercholesterolemia in rabbits25. Following oral administration of cholesterol to rabbits, elevations in serum cholesterol were prevented when feedings included alfalfa. Hyperlipidemia-induced rabbits fed alfalfa were found to have lower total cholesterol, specifically triglycerides and non-etherified fatty acids, when compared to rabbits not fed alfalfa. A study in 72 monkeys showed that diets consisting of alfalfa and cholesterol reduced cholesterol levels and atherosclerotic plaque formation when compared with diets containing cholesterol alone.

 

All herbs

Adenosma indianum - Aegle marmelos Correa - Aganosma marginata - Adenosma indianum - Allium satium - Allium tuberosum - Aloe vera - Alpinia galanga - Alpinia officinarum - Alstonia scholaris - Amomum krervanh - Andrographis paniculata - Arachis hypogaea - Boesenbergia pandurata - Bridelia burmanica - Canaga odorata - Capsicum annuum - Capsicum frutescens - Carica papaya - Carthamus tinctorius  - Cassia angustifolia - Cassia tora - Centella asiatica - Cinnamomum cassia - Clitoria ternatea - Coriandrum sativum - Curcuma Longa - Cymbopogon citratus - Eclipta prostrata - Elettaria cardamomum - Equisetum arvense  - Ganoderma lucidum - Ginkgo biloba - Glycine max - Hibiscus rosa-sinensis - Illicium verum - Jasmine - Lycium barbarum - Medicago sativa - Momordica charantia - Morinda officinalis - Moringa oliefera - Myristica fragrans - Nelumbo nucifera - Ocymum basilicum - Panax ginseng - Perilla frutescens - Phaseolus vulgaris - Phyllanthus emblica - Piper nigrum - Plumeriaalba - Plantago ovata - Ricinus - Sesamum indicum - Styrax tonkinense - Sassafras - Terminalia chebula  - Tribulus terrestris  - Zingiber officinale

Resources:
- Lavit KHAM  B.Sc (Chemistry),B.Pharm, MPS,MAACP, MNHAA
Medicinal Plants of Cambodia Habitat, Chemical constituents and Ethno botanical Uses
Bendigo Scientific Press   ISBN 0-646-43703-8  / 9780646437033
- Somanith BOUAMANIVONG & Onvilay SOURIYA Ministry of Health, Traditional Medicine Research Center, Editor Prof. Dr. Bouhong SOUTHAVONG, Vientiane 2005.
- Lily, M. PERRY. Medicinal Plants of East and Southeast Asia, London, England 1978
- WHO Regional Publications, Western Pacific Series No 2
- Jules VIDAL, Noms vernaculaires de plantes (LAO, MEO, KHA) 1959
- Medicinal Plants in China 1989
- C. Pierce SALGUERO A Thai Herbal, Traditional Recipes for Health and Harmony, 2005
Silkworm Books www.silkwormbooks.info   ISBN 974-9575-74-1 

Acknowledgements:
- Dr. Sabine WILKINS Plant Physiology & Dr. Pauline Mc CABE Naturopathy, La Trobe University, Melbourne, Victoria Australia.
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Prof. Roger KING, Pharmacology Toxicology, Monash University, Australia.
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Chea SOK MENG, Cambodian pharmacist
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Prof, Ka SUNBAUNAT Cambodian psychiatrist, Vice Dean, Faculty of Medicine, Phnom Penh.

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